Composition

Each 100 mL vial contains:

• Ciprofloxacin: 200 mg.
• Excipients: S.Q. for one vial.

Indications

Ciperf I.V. solution is indicated for the treatment of infections in adults only in the following conditions:

Urinary tract infections, lower respiratory infections, nosocomial pneumonia, skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections (used in conjunction with metronidazole).

Empirical therapy for febrile neutropenic patients in combination with piperacillin sodium.

Dosage and Administration

Ciprofloxacin I.V. is recommended for adults only.

• For urinary tract infections: according to severity of the infection the recommended dosage is 200-400 mg every 12 hours.
• For lower respiratory tract infections, skin and skin structure infections, and bone and joint infections of mild to moderate severity is 400mg I.V. every 12 hours, and for severe/complicated infections, the recommended dosage is 400mg every 8 hours.
• The recommended dosage for mild, moderate, and severe nosocomial pneumonia is 400 mg I.V. every 8 hours.
• Complicated intra-abdominal infections: 400mg I.V. every 12 hours, plus I.V. metronidazole to provide appropriate anaerobic coverage.

Ciprofloxacin I.V. should be administered by intravenous infusion over a period of 60 minutes, into a large vein.

Recommended dose for patients with impaired renal functions: