Description

Amolin exerts a broad spectrum bactericidal activity against  several G (+ ve) (bacillus anthracis – clostridium species – corynebacterium species – diplococcus pneumonia – staphylococcus aureus – streptococcus faecalis – streptococcus pyogenes – streptococcus viridans – listeria monocytogenes).

G (– ve) (bordetella pertussis – brucella species – Escherichia coli – haemophilus influenzae – neisseria meningitides – proteus mirabilis – salmonella species – shigella species – neisseria gonorrhoeae – vibrio cholera).

Composition

Each vial contains :

• Amoxicillin Na: 530 mg (equiv. to amoxicillin base 500 mg).
• Excipients: S.Q. for one vial.

Indications

Amolin (Amoxicillin) is indicated in the treatment of the following infections:

• Infections of the ( ear – nose – throat ).
• Infections of the urogenital tract.
• Infections of the skin and soft tissues.
• Infections of the lower respiratory tract.
• Sever infections ( septicemia – peritonitis – endocarditis – osteomyelitis ).
• Infections of the gastro-intestinal tract.
• Typhoid or paratyphoid fever
• Gonorrhoeae.

Amolin has been used as an alternative to chloramphenicol in the treatment of infections caused by salmonella typhi.

Amolin is used in infections of the biliary-tract, to achieve high concentrations in the bile.

Dosage & Administration

Method of Administration

• Moderate infections:  500mg/ 8 Hr. I.M.
• Severe infections:
  • 1 g/ 6 Hr. I.V ( 3 – 4 ) minutes.
  • 1 g/ 6 Hr. infusion (30- 60) minutes.
• Children up to 10 years of age: 50 – 100 mg/kg I.M daily by injections in divided doses.

Method of Vial Dissolving

• Dissolve 250 mg , 500 mg vials in 2 ml water for injection.
• Dissolve 1000 mg vial in 4 ml water for injection.